A population-scale immune multiome atlas identifies regulatory mechanisms involved in disease.

What it means

This Nature paper presents a population-scale atlas of immune cells that simultaneously profiles chromatin accessibility and gene expression across thousands of individuals. By integrating these multi-omic data, the study identifies how disease-associated genetic variants regulate gene expression through chromatin changes, revealing mechanistic pathways for immune-related diseases.

Accuracy & sourcesSourced

The claim is based on a peer-reviewed Nature paper, which is the primary source. The paper presents original data and analysis, making the findings authoritative within the scope of the study.

How new

Genuinely new; the paper was published in Nature within the last day.

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• Nature (current) — first to publish