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THU, 24 SEPT · 98 ITEMS
"Hepatocytes promote liver metastasis of pancreatic cancer by providing serine" — Nature (current) · Science & Medicine
This Nature paper reports that (liver cells) supply the amino acid to pancreatic cancer cells that have metastasized to the liver, thereby promoting their growth. The study identifies a metabolic dependency in liver metastases of pancreatic ductal adenocarcinoma (PDAC) that lack the ability to synthesize serine themselves, suggesting a potential therapeutic vulnerability.
The claim is based on a peer-reviewed study published in Nature, a top-tier scientific journal, making it highly credible. The primary source is the actual research paper (doi:10.1038/s41586-026-11051-z), and the reporting sits directly on that source.
The paper was published on September 23, 2026, making this genuinely new research.
We covered a study on MTFP1 driving pancreatic cancer liver in Gut (February 2026), which explores a different molecular mechanism (mitochondrial dynamics) for the same clinical problem.