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MON, 26 OCT · 94 ITEMS
"Low-dose aspirin linked to 70% lower dementia risk in specific genotype" — Science Daily (all) · Science & Medicine
A new genetic analysis of a large clinical trial in older adults found that taking daily low-dose aspirin was associated with a 70% lower risk of developing dementia, but only among people with a specific genetic profile related to platelet function. For those without this , aspirin showed no significant benefit. The finding suggests that aspirin's potential to prevent dementia may depend on an individual's genetic makeup, highlighting the importance of personalized approaches to dementia prevention.
The claim is based on a post-hoc genetic analysis of a randomized controlled trial (likely the ASPREE trial), which is a credible but exploratory finding. The primary source is a peer-reviewed study, and the reporting by Science Daily accurately reflects the study's conclusions, though post-hoc analyses are considered less definitive than pre-specified analyses.
This is genuinely new research, with the study being published and reported in late October 2026.